Second Chance at Life for Adult Stem Cell Transplant Patient

February 17th, 2011 by admin

by David Prentice

An update on the City of Hope’s 10,000th bone marrow adult stem cell transplant. The patient, now identified as 51-year-old William Fuller, was released from the hospital last week. The father of three, a small-business owner, was born in Belize and came to the U.S. in 1982. When he had his adult stem cell transplant on Jan. 13, 2011, his nurse wished him “Happy Birthday,” signaling the beginning of his new life.

According to Dr. Stephen J. Forman at City of Hope:

“Mr. Fuller is the poster child for what we do. There are thousands of other people like him who have been helped because a donor came forward to provide lifesaving stem cells that allowed us to do a transplant and hopefully cure the disease. Every patient who gets through a transplant here is the beneficiary of a lot of laboratory work and hard thinking that’s gone into trying to solve the problem – how to best cure the cancer in the safest way possible.”

Dr. Forman noted many patients view their adult stem cell donors as new members of their family, and often develop lifelong relationships. “They are ‘blood relatives,’” he said.

Mr. Fuller credited his sister, Karen Hyde, as being instrumental in arranging bone marrow drives in California, Florida and New York with the help of “Be the Match,” the national marrow donor program.

Adult stem cells continue to save thousands of lives every year.

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You can learn to save lives using Sarver Heart Center’s Continuous Chest Compression CPR

February 14th, 2011 by admin
Call 911 and start doing chest compressions immediately

Call 911 and start doing chest compressions immediately

Click here to watch this five minute video and then you will know what to do if someone appears to be having a heart attack.

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Evey minute you delay beginning CPR, lessens their chance of surviving by 10 percent.  If you wait 5 minutes their chance of survival has already dropped to 50 percent or less.

“Sarver Heart Center’s newest video makes it easy to learn Continuous Chest Compression CPR. Every three days, more Americans die from sudden cardiac arrest than the number who died in the 9-11 attacks. You can lessen this recurring loss by learning this hands-only CPR method that doubles a person’s chance of surviving cardiac arrest.  Watch physician researchers Gordon A. Ewy, MD, and Karl Kern, MD, demonstrate the easy, life-saving method that they developed at the University of Arizona College of Medicine.” If you would like to attend a CPR class check out these CPR classes in Houston.

Click here to learn how easy it is to administer life-saving Sarver Chest Compressions

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Study finds that the pesticides rotenone and paraquat are associated with Parkinson’s disease

February 11th, 2011 by admin


National Institutes of Health research shows a link between use of two pesticides, rotenone and paraquat, and Parkinson’s disease. People who used either pesticide developed Parkinson’s disease approximately 2.5 times more often than non-users.

The study was a collaborative effort conducted by researchers at the National Institute of Environmental Health Sciences (NIEHS), which is part of the National Institutes of Health, and the Parkinson’s Institute and Clinical Center in Sunnyvale, Calif.

“Rotenone directly inhibits the function of the mitochondria, the structure responsible for making energy in the cell,” said Freya Kamel, Ph.D., a researcher in the intramural program at NIEHS and co-author of the paper appearing online in the journal Environmental Health Perspectives. “Paraquat increases production of certain oxygen derivatives that may harm cellular structures. People who used these pesticides or others with a similar mechanism of action were more likely to develop Parkinson’s disease.

The authors studied 110 people with Parkinson’s disease and 358 matched controls from the Farming and Movement Evaluation (FAME) Study (http://www.niehs.nih.gov/research/atniehs/labs/epi/studies/fame/index.cfm) to investigate the relationship between Parkinson’s disease and exposure to pesticides or other agents that are toxic to nervous tissue. FAME is a case-control study that is part of the larger Agricultural Health Study (http://www.niehs.nih.gov/research/atniehs/labs/epi/studies/ahs/index.cfm), a study of farming and health in approximately 90,000 licensed pesticide applicators and their spouses. The investigators diagnosed Parkinson’s disease by agreement of movement disorder specialists and assessed the lifelong use of pesticides using detailed interviews.

There are no home garden or residential uses for either paraquat or rotenone currently registered. Paraquat use has long been restricted to certified applicators, largely due to concerns based on studies of animal models of Parkinson’s disease. Use of rotenone as a pesticide to kill invasive fish species is currently the only allowable use of this pesticide.

“These findings help us to understand the biologic changes underlying Parkinson’s disease. This may have important implications for the treatment and ultimately the prevention of Parkinson’s disease,” said Caroline Tanner, M.D., Ph.D., clinical research director of the Parkinson’s Institute and Clinical Center, and lead author of the article.

The NIEHS supports research to understand the effects of the environment on human health and is part of NIH. For more information on environmental health topics, visit www.niehs.nih.gov. Subscribe to one or more of the NIEHS news lists (www.niehs.nih.gov/news/releases/newslist/index.cfm) to stay current on NIEHS news, press releases, grant opportunities, training, events, and publications.

The National Institutes of Health (NIH) — The Nation’s Medical Research Agency — includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.


Reference: Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, Marras C, Bhudhikanok GS, Kasten M, Chade AR, Comyns K, Richards MB, Meng C, Priestly B, Fernandez HH, Cambi F, Umbach DM, Blair A, Sandler DP, Langston JW. 2011. Rotenone, paraquat and Parkinson’s disease. Environ Health Perspect; doi:10.1289/ehp.1002839 [Online 26 January 2011].

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